General links

• Cardiovascular GO Annotation Initiative [external website] : Home page for the Cardiovascular GO Annotation Initiative
• GO Consortium : Home page for the GO consortium
• GO Annotation Guide: Guide to annotating with GO terms, important for annotation consistency
• GO Evidence Codes : Guide to GO evidence codes
• GOA database [external website] : Gene Ontology Annotation database at EBI home page, download from the GOA ftp site, see statistics and release news
• BHF-UCL list of 4000 cardiovascular-associated genes [external website]
• Cardiovascular-associated genes prioritised for annotation[external website] by the Cardiovascular GO Annotation Initiative

Cardiovascular GO Annotation Initiative Newsletter

• Issue 3, October 2008 [external website]>
• Issue 2, July 2008 [external website]>
• Issue 1, April 2008 [external website]>

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Outreach

• Cardiovascular Community Annotation Wiki : Enables scientists and annotators to exchange information on a gene by gene basis.
• Cardiovascular interest group mailing list: Please register to be kept up to date on GO annotation progress, GO development discussions, forthcoming workshops, etc..
• SourceForge Request Tracker [external website] : Login and request ontology amendments with the GO editorial office

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GO tools

GO browsers

• QuickGO [external website] : Search and display GO terms or GO annotations via specific UniProtKB accessions, more functionality coming soon
• AmiGO : Find GO terms, filters for species, datasource or evidence codes available, more functionality coming soon

Sequence searches

• Sequence Retrieval Service [external website] (SRS) : Database search tool to query GO, GOA, UniProtKB, IPI allowing the linking of datasets and the creation of customised views
• Integr8 [external website] : Features include ability to search for sequences associated with a particular GO:ID
• Entrez Gene [external website] : NCBI search tool, used to find gene records with wide range of annotations and links including GO
• Mouse Genome Informatics [external website] : MGI search tool, use to find gene record with wide range of annotations and links
• UniProt [external website] : UniProt Consortium search tool, can query UniProtKB, UniParc and UniRef

BLAST searches

• AmiGO Blast : BLAST search shows the associated GO terms for each hit. Useful for finding GO terms associated with homologues
• MPsrch [external website] : BLAST search which returns UniProtKB/UniParc/IPI accession IDs
• NCBI BLASTP [external website] : Protein BLAST with options for UniProtKB/SwissProt or NCBI database search

Literature search tools

• CiteXplore [external website] : Literature search and text mining tool. Can highlight abstracts to show potential GO terms and links gene names to UniProtKB records, a quick way of finding accessions.
• Whatizit [external website] : Can paste in any text for highlighting with potential GO terms and links gene names to UniProtKB records

Mapping tools

• iHOP [external website] : Links together protein information; search using gene symbol or accession ID.
• GOPubMed [external website] : Literature search which uses a GO to Mesh manual mapping, GO terms highlighted in abstracts, useful statistics for identifying immune gene experts
• GO Term Finder [external website] : Find significant GO terms shared among a list of genes from your organism.
• GO Term Mapper [external website] : Map granular GO annotations for genes in a list to a set of broader high-level GO term parents, allowing you to bin your genes into broad categories

For more annotation and gene expression analysis tools, please see the GO tools pages.

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